In Sympy gamma, you can calculate x^2 by using the pow() function with the base x and the exponent 2. For example, if you want to calculate x^2 where x is a variable, you can use the pow(x, 2) function. This will raise x to the power of 2 and give you the result. Alternatively, you can also use the ** operator to calculate x^2. For example, you can write x**2 to get the square of x. Both methods will give you the square of x in Sympy gamma.